Original paper
Functional Proteomic Profiling of Secreted Serine Proteases in Health and Inflammatory Bowel Disease
Abstract
While proteases are essential in gastrointestinal physiology, accumulating evidence indicates that dysregulated proteolysis plays a pivotal role in the pathophysiology of inflammatory bowel disease (IBD). Nonetheless, the identity of overactive proteases released by human colonic mucosa remains largely unknown. Studies of protease abundance have primarily investigated expression profiles, not taking into account their enzymatic activity. Herein...
Paper Details
Title
Functional Proteomic Profiling of Secreted Serine Proteases in Health and Inflammatory Bowel Disease
Published Date
May 18, 2018
Journal
Volume
8
Issue
1
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Notes
History