Metabolic reprogramming of Kaposi’s sarcoma associated herpes virus infected B-cells in hypoxia

Volume: 14, Issue: 5, Pages: e1007062 - e1007062
Published: May 10, 2018
Abstract
Kaposi’s sarcoma associated herpesvirus (KSHV) infection stabilizes hypoxia inducible factors (HIFs). The interaction between KSHV encoded factors and HIFs plays a critical role in KSHV latency, reactivation and associated disease phenotypes. Besides modulation of large-scale signaling, KSHV infection also reprograms the metabolic activity of infected cells. However, the mechanism and cellular pathways modulated during these changes are poorly...
Paper Details
Title
Metabolic reprogramming of Kaposi’s sarcoma associated herpes virus infected B-cells in hypoxia
Published Date
May 10, 2018
Volume
14
Issue
5
Pages
e1007062 - e1007062
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