Original paper
Designer cells programming quorum-sensing interference with microbes
Abstract
Quorum sensing is a promising target for next-generation anti-infectives designed to address evolving bacterial drug resistance. The autoinducer-2 (AI-2) is a key quorum-sensing signal molecule which regulates bacterial group behaviors and is recognized by many Gram-negative and Gram-positive bacteria. Here we report a synthetic mammalian cell-based microbial-control device that detects microbial chemotactic formyl peptides through a formyl...
Paper Details
Title
Designer cells programming quorum-sensing interference with microbes
Published Date
May 2, 2018
Journal
Volume
9
Issue
1