Genetic correlation of antisocial behaviour with alcohol, nicotine, and cannabis use

There is high comorbidity between antisocial behaviour (ASB) and substance use, and twin studies have shown that part of the covariation is due to overlapping genetic influences. Here we used measured genetic effects to estimate the genetic correlations of ASB with nicotine, alcohol, and cannabis use. We meta-analysed data from two genome-wide association studies for ASB and used existing summary statistics from the largest genome-wide...