Radiomics Evaluation of Histological Heterogeneity Using Multiscale Textures Derived From 3D Wavelet Transformation of Multispectral Images

Purpose: Colorectal cancer (CRC) is markedly heterogeneous and develops progressively towards malignancy through several stages which include stroma (ST), benign hyperplasia (BH), intraepithelial neoplasia (IN) or precursor cancerous lesion and carcinoma (CA). Identification of the malignancy stage of CRC pathology tissues allows the most appropriate therapeutic intervention. Methods: This study investigates multiscale texture features extracted...