Nucleic acids delivering nucleic acids

Volume: 134, Pages: 79 - 93
Published: Sep 1, 2018
Abstract
Nucleic acid therapeutics, including siRNAs, miRNAs/antimiRs, gRNAs and ASO, represent innovative and highly promising molecules for the safe treatment of a wide range of pathologies. The efficiency of systemic treatments is impeded by 1) the need to overcome physical and functional barriers in the organism, and 2) to accumulate in the intracellular active site at therapeutic concentrations. Although oligonucleotides either as modified naked...
Paper Details
Title
Nucleic acids delivering nucleic acids
Published Date
Sep 1, 2018
Volume
134
Pages
79 - 93
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