Intestinal Failure and Aberrant Lipid Metabolism in Patients With DGAT1 Deficiency
Abstract
Background & AimsCongenital diarrheal disorders are rare inherited intestinal disorders characterized by intractable, sometimes life-threatening, diarrhea and nutrient malabsorption; some have been associated with mutations in diacylglycerol-acyltransferase 1 (DGAT1), which catalyzes formation of triacylglycerol from diacylglycerol and acyl-CoA. We investigated the mechanisms by which DGAT1 deficiency contributes to intestinal failure using...
Paper Details
Title
Intestinal Failure and Aberrant Lipid Metabolism in Patients With DGAT1 Deficiency
Published Date
Jul 1, 2018
Journal
Volume
155
Issue
1
Pages
130 - 143.e15
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Notes
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