Successful reprogramming of cellular protein production through mRNA delivered by functionalized lipid nanoparticles

Abstract
The development of safe and efficacious gene vectors has limited greatly the potential for therapeutic treatments based on messenger RNA (mRNA). Lipid nanoparticles (LNPs) formed by an ionizable cationic lipid (here DLin-MC3-DMA), helper lipids (distearoylphosphatidylcholine, DSPC, and cholesterol), and a poly(ethylene glycol) (PEG) lipid have been identified as very promising delivery vectors of short interfering RNA (siRNA) in different...
Paper Details
Title
Successful reprogramming of cellular protein production through mRNA delivered by functionalized lipid nanoparticles
Published Date
Mar 27, 2018
Volume
115
Issue
15
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.