Dentate granule cell recruitment of feedforward inhibition governs engram maintenance and remote memory generalization

Volume: 24, Issue: 4, Pages: 438 - 449
Published: Mar 12, 2018
Abstract
Dynamic regulation of the cytoskeletal factor ABLIM3 controls the precision of memory representations in rodent models of post-traumatic stress disorder and age-related cognitive impairment. Memories become less precise and generalized over time as memory traces reorganize in hippocampal–cortical networks. Increased time-dependent loss of memory precision is characterized by an overgeneralization of fear in individuals with post-traumatic stress...
Paper Details
Title
Dentate granule cell recruitment of feedforward inhibition governs engram maintenance and remote memory generalization
Published Date
Mar 12, 2018
Volume
24
Issue
4
Pages
438 - 449
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