Last. Antoine Dufour(UoC: University of Calgary)H-Index: 7
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Although critical for host defense, innate immune cells are also pathologic drivers of acute respiratory distress syndrome (ARDS). Innate immune dynamics during Coronavirus Disease 2019 (COVID-19) ARDS, compared to ARDS from other respiratory pathogens, is unclear. Moreover, mechanisms underlying the beneficial effects of dexamethasone during severe COVID-19 remain elusive. Using single-cell RNA sequencing and plasma proteomics, we discovered that, compared to bacterial ARDS, COVID-19 was associ...
Bifidobacterium species enriched in breastfed infants produce metabolites that strengthen infants’ gut barrier and immune systems. Bifidobacterium species enriched in breastfed infants produce metabolites that strengthen infants’ gut barrier and immune systems.
Last. Lawrence A. Tabak(NIH: National Institutes of Health)H-Index: 62
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The National Institutes of Health (NIH) is committed to increasing the participation of underrepresented groups in science and medicine, through changes in our funding and recruitment processes. These actions provide a blueprint for the global research community.
Last. Ryan J. Tedford(MUSC: Medical University of South Carolina)H-Index: 32
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SGLT-2 inhibitors show promise for treatment of heart failure with preserved ejection fraction, but clinical data are nuanced. Appropriate endpoint selection will be key to deciphering their benefits.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is rarely fatal in children and young people (CYP, <18 years old), but quantifying the risk of death is challenging because CYP are often infected with SARS-CoV-2 exhibiting no or minimal symptoms. To distinguish between CYP who died as a result of SARS-CoV-2 infection and those who died of another cause but were coincidentally infected with the virus, we undertook a clinical review of all CYP deaths with a positive SARS-CoV-...
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