Cancer evolution, mutations, and clonal selection in relapse neuroblastoma
Abstract
The notion of cancer as a complex evolutionary system has been validated by in-depth molecular analyses of tumor progression over the last years. While a complex interplay of cell-autonomous programs and cell-cell interactions determines proliferation and differentiation during normal development, intrinsic and acquired plasticity of cancer cells allow for evasion of growth factor limitations, apoptotic signals, or attacks from the immune...
Paper Details
Title
Cancer evolution, mutations, and clonal selection in relapse neuroblastoma
Published Date
Feb 24, 2018
Journal
Volume
372
Issue
2
Pages
263 - 268
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Notes
History