Original paper
Mechanism of action of cytotoxic compounds from the seeds of Euphorbia lathyris
Abstract
The seeds of Euphorbia lathyris are used in traditional Chinese medicines for the treatment of various medical conditions. E. lathyris contains many natural diterpenes with a lathyrane skeleton.Five lathyrane-type diterpenoids named Euphorbia factors L1, L2, L3, L8, and L9 (1-5), were investigated for cytotoxicity against A549, MDA-MB-231, KB, and MCF-7 cancer cell lines and the KB-VIN multidrug resistant (MDR) cancer cell line. Also, a tetraol...
Paper Details
Title
Mechanism of action of cytotoxic compounds from the seeds of Euphorbia lathyris
Published Date
Mar 1, 2018
Journal
Volume
41
Pages
62 - 66
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Notes
History