Review paper
Memory formation depends on both synapse-specific modifications of synaptic strength and cell-specific increases in excitability
Abstract
The modification of synaptic strength produced by long-term potentiation (LTP) is widely thought to underlie memory storage. Indeed, given that hippocampal pyramidal neurons have >10,000 independently modifiable synapses, the potential for information storage by synaptic modification is enormous. However, recent work suggests that CREB-mediated global changes in neuronal excitability also play a critical role in memory formation. Because these...
Paper Details
Title
Memory formation depends on both synapse-specific modifications of synaptic strength and cell-specific increases in excitability
Published Date
Feb 12, 2018
Journal
Volume
21
Issue
3
Pages
309 - 314
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History