The long tail of oncogenic drivers in prostate cancer
Abstract
Comprehensive genomic characterization of prostate cancer has identified recurrent alterations in genes involved in androgen signaling, DNA repair, and PI3K signaling, among others. However, larger and uniform genomic analysis may identify additional recurrently mutated genes at lower frequencies. Here we aggregate and uniformly analyze exome sequencing data from 1,013 prostate cancers. We identify and validate a new class of E26...
Paper Details
Title
The long tail of oncogenic drivers in prostate cancer
Published Date
Apr 2, 2018
Journal
Volume
50
Issue
5
Pages
645 - 651
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