Original paper
α-Catenin-dependent cytoskeletal tension controls Yap activity in the heart
Abstract
Shortly after birth, muscle cells of the mammalian heart lose their ability to divide. At the same time, the N-cadherin/catenin cell adhesion complex accumulates at the cell termini, creating a specialized type of cell-cell contact called the intercalated disc (ICD). To investigate the relationship between ICD maturation and proliferation, αE-catenin (Ctnna1) and αT-catenin (Ctnna3) genes were deleted to generate cardiac-specific α-catenin...
Paper Details
Title
α-Catenin-dependent cytoskeletal tension controls Yap activity in the heart
Published Date
Feb 22, 2018
Journal
Volume
145
Issue
5