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Review paper

Beyond motor neurons: expanding the clinical spectrum in Kennedy’s disease

Volume: 89, Issue: 8, Pages: 808 - 812
Published: Jan 20, 2018
Abstract
Kennedy's disease, or spinal and bulbar muscular atrophy (SBMA), is an X-linked neuromuscular condition clinically characterised by weakness, atrophy and fasciculations of the limb and bulbar muscles, as a result of lower motor neuron degeneration. The disease is caused by an abnormally expanded triplet repeat expansions in the ubiquitously expressed androgen receptor gene, through mechanisms which are not entirely elucidated. Over the years...
Paper Details
Title
Beyond motor neurons: expanding the clinical spectrum in Kennedy’s disease
Published Date
Jan 20, 2018
Volume
89
Issue
8
Pages
808 - 812
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