Can T₁w/T₂w ratio be used as a myelin‐specific measure in subcortical structures? Comparisons between FSE‐based T₁w/T₂w ratios, GRASE‐based T₁w/T₂w ratios and multi‐echo GRASE‐based myelin water fractions

Given the growing popularity of T 1 ‐weighted/ T 2 ‐weighted ( T 1 w/ T 2 w) ratio measurements, the objective of the current study was to evaluate the concordance between T 1 w/ T 2 w ratios obtained using conventional fast spin echo (FSE) versus combined gradient and spin echo (GRASE) sequences for T 2 w image acquisition, and to compare the resulting T 1 w/ T 2 w ratios with histologically validated myelin water fraction (MWF) measurements in...