Do ketone bodies mediate the anti-seizure effects of the ketogenic diet?
Abstract
Although the mechanisms underlying the anti-seizure effects of the high-fat ketogenic diet (KD) remain unclear, a long-standing question has been whether ketone bodies (i.e., β-hydroxybutyrate, acetoacetate and acetone), either alone or in combination, contribute mechanistically. The traditional belief has been that while ketone bodies reflect enhanced fatty acid oxidation and a general shift toward intermediary metabolism, they are not likely...
Paper Details
Title
Do ketone bodies mediate the anti-seizure effects of the ketogenic diet?
Published Date
May 1, 2018
Journal
Volume
133
Pages
233 - 241
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