SIDR: simultaneous isolation and parallel sequencing of genomic DNA and total RNA from single cells

Volume: 28, Issue: 1, Pages: 75 - 87
Published: Dec 5, 2017
Abstract
Simultaneous sequencing of the genome and transcriptome at the single-cell level is a powerful tool for characterizing genomic and transcriptomic variation and revealing correlative relationships. However, it remains technically challenging to analyze both the genome and transcriptome in the same cell. Here, we report a novel method for simultaneous isolation of genomic DNA and total RNA (SIDR) from single cells, achieving high recovery rates...
Paper Details
Title
SIDR: simultaneous isolation and parallel sequencing of genomic DNA and total RNA from single cells
Published Date
Dec 5, 2017
Volume
28
Issue
1
Pages
75 - 87
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