Drug hypersensitivity: We need to do more

Drug hypersensitivity reactions (DHRs) are drug-induced immune and/or inflammatory reactions. They go beyond classical IgE-mediated reactions, such as anaphylaxis, and comprise many T cell–mediated reactions, which altogether are likely more common than IgE reactions. DHRs are an important clinical issue and are frequent, even if DHRs to a single drug might be rare. The clinician is usually confronted with a particular clinical situation and has...