Diagnostic Potential of Neural Exosome Cargo as Biomarkers for Acute Brain Injury

Objective Neuronal exosomes purified from peripheral blood samples have been proposed as diagnostic tool in the setting of acute brain injury but never tested clinically. We hypothesized that exosome protein biomarkers would change over time following acute hypoxic brain injury and would predict response to therapy. Methods Synaptopodin ( SYNPO ), an actin‐associated protein present in postsynaptic spines, was evaluated as a potential biomarker...