Myostatin and beyond in cirrhosis: all roads lead to sarcopenia

Sarcopenia or loss of skeletal muscle mass is a major complication of cirrhosis and liver disease.1-6 A large body of literature exists to support the prognostic significance of sarcopenia in cirrhosis.1, 2, 5, 7 Independent clinical consequences of sarcopenia in cirrhosis include lower survival and quality of life, increases risk of complications including infections and encephalopathy, and lower post liver transplant survival.1-5, 7-9...