Review paper
Vectored gene delivery for lifetime animal contraception: Overview and hurdles to implementation
Abstract
There is a need for permanent, non-surgical methods of contraception for many animal species. Here we discuss the hypothesis that transgene-mediated expression of fertility inhibiting molecules such as monoclonal antibodies, ligands for cell surface receptors, receptor decoys, or small RNAs can provide such a method, which we term vectored contraception. We outline the technologies involved, progress made, and discuss challenges to...
Paper Details
Title
Vectored gene delivery for lifetime animal contraception: Overview and hurdles to implementation
Published Date
May 1, 2018
Journal
Volume
112
Pages
63 - 74
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Notes
History