Estrogen is an important mediator of mast cell activation in ovarian endometriomas
Abstract
Endometriosis is an estrogen-dependent disease. Previous research has shown that abnormal enzymes associated with estrogen (E2) metabolism and an increased number of mast cells (MCs) in endometriomas are implicated in the pathogenesis of endometriosis. However, it remains unclear how MCs mediate the role of E2 in endometriosis. Accordingly, we investigated whether E2 was associated with the number of MCs, and the rate of degranulation, in local...
Paper Details
Title
Estrogen is an important mediator of mast cell activation in ovarian endometriomas
Published Date
Jan 1, 2018
Journal
Volume
155
Issue
1
Pages
73 - 83
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