Review paper
Tissue Force Programs Cell Fate and Tumor Aggression
Abstract
Biomechanical and biochemical cues within a tissue collaborate across length scales to direct cell fate during development and are critical for the maintenance of tissue homeostasis. Loss of tensional homeostasis in a tissue not only accompanies malignancy but may also contribute to oncogenic transformation. High mechanical stress in solid tumors can impede drug delivery and may additionally drive tumor progression and promote metastasis....
Paper Details
Title
Tissue Force Programs Cell Fate and Tumor Aggression
Published Date
Nov 1, 2017
Journal
Volume
7
Issue
11
Pages
1224 - 1237
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Notes
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