Pseudo-CT generation by conditional inference random forest for MRI-based radiotherapy treatment planning

Dose calculation from MRI is a topical issue. New treatment systems combining a linear accelerator with a MRI have been recently being developed. MRI has good soft tissue contrast without ionizing radiation exposure. However, unlike CT, MRI does not provide electron density information necessary for dose calculation. We propose in this paper a machine learning method to simulate a CT from a target MRI and co-registered CT-MRI training set. Ten...