Extended venous thromboembolism prophylaxis comparing rivaroxaban to aspirin following total hip and knee arthroplasty

Deep vein thrombosis and pulmonary embolism are common complications post-total hip (THA) and total knee arthroplasty (TKA). Prophylaxis with direct oral anticoagulants, such as rivaroxaban extended beyond hospital discharged is commonly prescribed for the prevention of these complications. We reasoned aspirin (ASA) potentially would be an attractive alternative agent for extended prophylaxis because of its low cost, convenience and few side...