Effect of Lactobacillus paracasei CNCM I‐1572 on symptoms, gut microbiota, short chain fatty acids, and immune activation in patients with irritable bowel syndrome: A pilot randomized clinical trial

Background Evidence suggests a role of intestinal microbiota‐host interactions in the pathophysiology and symptoms of irritable bowel syndrome (IBS). Objective The objective of this article is to assess the effects of Lactobacillus paracasei CNCM I‐1572 on clinical and gut microbiota‐related factors in IBS. Methods We conducted a multicenter, randomized, double‐blind, cross‐over, 18‐week, placebo‐controlled, pilot trial assessing the effect of...