Development of the combined positive score (CPS) for the evaluation of PD-L1 in solid tumors with the immunohistochemistry assay PD-L1 IHC 22C3 pharmDx.

Volume: 35, Issue: 15_suppl, Pages: e14589 - e14589
Published: May 20, 2017
Abstract
e14589 Background: Developing clinically relevant and highly reproducible scoring methods for PD-L1 to identify patients who will respond effectively to anti-PD-1 therapy is key in the development of companion or complementary diagnostic assays. Methods: Scoring method for PD-L1 IHC 22C3 pharmDx in NSCLC have only captured the percentage on stained tumor cells using the tumor proportion score (TPS) (Roach et al. 2016, Appl Immunohistochem Mol...
Paper Details
Title
Development of the combined positive score (CPS) for the evaluation of PD-L1 in solid tumors with the immunohistochemistry assay PD-L1 IHC 22C3 pharmDx.
Published Date
May 20, 2017
Volume
35
Issue
15_suppl
Pages
e14589 - e14589
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