Original paper
The antibody–drug conjugate target landscape across a broad range of tumour types
Abstract
BackgroundAntibody–drug conjugates (ADCs), consisting of an antibody designed against a specific target at the cell membrane linked with a cytotoxic agent, are an emerging class of therapeutics. Because ADC tumour cell targets do not have to be drivers of tumour growth, ADCs are potentially relevant for a wide range of tumours currently lacking clear oncogenic drivers. Therefore, we aimed to define the landscape of ADC targets in a broad range...
Paper Details
Title
The antibody–drug conjugate target landscape across a broad range of tumour types
Published Date
Dec 1, 2017
Journal
Volume
28
Issue
12
Pages
3083 - 3091
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Notes
History