Original paper
Reversible retinal vessel closure from VEGF-induced leukocyte plugging
Abstract
Clinical trials in patients with macular edema due to diabetic retinopathy or retinal vein occlusion (RVO) have shown that suppression of VEGF not only improves macular edema, but also reopens closed retinal vessels, prevents progression of vessel closure, and improves retinopathy. In this study, we show the molecular basis for those clinical observations. Increased retinal levels of VEGF in mice cause plugging of retinal vessels with...
Paper Details
Title
Reversible retinal vessel closure from VEGF-induced leukocyte plugging
Published Date
Sep 21, 2017
Journal
Volume
2
Issue
18
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Notes
History