This website uses cookies.
We use cookies to improve your online experience. By continuing to use our website we assume you agree to the placement of these cookies.
To learn more, you can find in our Privacy Policy.
Original paper

Fibroblast-specific inhibition of TGF-β1 signaling attenuates lung and tumor fibrosis

Volume: 127, Issue: 10, Pages: 3675 - 3688
Published: Sep 4, 2017
Abstract
TGF-β1 signaling is a critical driver of collagen accumulation and fibrotic disease but also a vital suppressor of inflammation and epithelial cell proliferation. The nature of this multifunctional cytokine has limited the development of global TGF-β1 signaling inhibitors as therapeutic agents. We conducted phenotypic screens for small molecules that inhibit TGF-β1–induced epithelial-mesenchymal transition without immediate TGF-β1 receptor (TβR)...
Paper Details
Title
Fibroblast-specific inhibition of TGF-β1 signaling attenuates lung and tumor fibrosis
Published Date
Sep 4, 2017
Volume
127
Issue
10
Pages
3675 - 3688
© 2025 Pluto Labs All rights reserved.
Step 1. Scroll down for details & analytics related to the paper.
Discover a range of citation analytics, paper references, a list of cited papers, and more.