Original paper
In aged primary T cells, mitochondrial stress contributes to telomere attrition measured by a novel imaging flow cytometry assay
Abstract
Summary The decline of the immune system with age known as immune senescence contributes to inefficient pathogen clearance and is a key risk factor for many aged‐related diseases. However, reversing or halting immune aging requires more knowledge about the cell biology of senescence in immune cells. Telomere shortening, low autophagy and mitochondrial dysfunction have been shown to underpin cell senescence. While autophagy has been found to...
Paper Details
Title
In aged primary T cells, mitochondrial stress contributes to telomere attrition measured by a novel imaging flow cytometry assay
Published Date
Aug 19, 2017
Journal
Volume
16
Issue
6
Pages
1234 - 1243