Review paper
HER2-positive breast cancer is lost in translation: time for patient-centered research
Abstract
No biomarker beyond HER2 itself, which suffers from a low positive predictive value, has demonstrated clinical utility in breast cancer, despite numerous attempts to improve treatment tailoring for the growing number of anti-HER2 targeted therapies. This prompted us to examine the body of evidence, using a systematic approach, to identify putative predictive biomarkers in HER2-positive breast cancer, and discuss the hitherto failure to address...
Paper Details
Title
HER2-positive breast cancer is lost in translation: time for patient-centered research
Published Date
Aug 1, 2017
Volume
14
Issue
11
Pages
669 - 681
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