Nature Reviews Clinical Oncology
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#1Alex Friedlaender (Geneva College)H-Index: 13
#2Vivek Subbiah (University of Texas MD Anderson Cancer Center)H-Index: 48
Last. Alfredo Addeo (Geneva College)H-Index: 21
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#1David T. Teachey (UPenn: University of Pennsylvania)H-Index: 56
#2Stephen P. Hunger (UPenn: University of Pennsylvania)H-Index: 97
Chimeric antigen receptor (CAR) T cells have remarkable efficacy in patients with B cell acute lymphoblastic leukaemia (ALL), but have not been successful to date in patients with T cell ALL (T-ALL). Now, data from Pan and colleagues demonstrate the safety and impressive short-term efficacy of allogeneic donor-derived anti-CD7 CAR T cells in an early-phase clinical trial involving patients with relapsed and/or refractory T-ALL.
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