Original paper
Abstract LB-122: Tumor heterogeneity in castration resistant neuroendocrine prostate cancer from whole exome sequencing of circulating tumor DNA
Abstract
Background: We recently identified mechanisms underlying the clonal evolution of castration resistant prostate adenocarcinoma (CRPC-Adeno) to a neuroendocrine resistance phenotype (Beltran et al, Nature Med 2016). In the current study, we aimed to develop a non-invasive approach to identify patients that are developing neuroendocrine prostate cancer (NEPC). Methods: We performed whole exome sequencing (WES) of matched circulating tumor DNA...
Paper Details
Title
Abstract LB-122: Tumor heterogeneity in castration resistant neuroendocrine prostate cancer from whole exome sequencing of circulating tumor DNA
Published Date
Jul 1, 2017
Journal
Volume
77
Issue
13_Supplement
Pages
LB - 122
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Notes
History