G-Quadruplexes: Prediction, Characterization, and Biological Application

Recent methodological advances allow us to study G-quadruplex structures at higher resolution and throughput. Approaches to use G-quadruplex structures as molecular tools are highlighted. Computational and experimental methods for G-quadruplex studies are reviewed. The works reviewed herein provide unique insights to explore the biological roles and uses of G-quadruplexes in basic and applied research. Guanine (G)-rich sequences in nucleic acids...