Diastolic hypotension due to intensive blood pressure therapy: Is it harmful?

Background and aims Reducing the diastolic blood pressure (DBP) below a certain threshold may lead to inadequate organ perfusion. This raises some concerns, because pharmacotherapy reduces both systolic and diastolic pressure. We aimed to investigate whether a pathway from intensive systolic blood pressure (SBP) treatment influences cardiovascular outcomes by inducing too low DBP. Methods We had access to data from the Systolic Blood Pressure...