Clinical Implications of the 2016 International Study Group on Pancreatic Surgery Definition and Grading of Postoperative Pancreatic Fistula on 775 Consecutive Pancreatic Resections.

Published on Jul 1, 2017in Annals of Surgery10.13
· DOI :10.1097/SLA.0000000000002362
Alessandra Pulvirenti11
Estimated H-index: 11
,
Giovanni Marchegiani29
Estimated H-index: 29
+ 7 AuthorsClaudio Bassi110
Estimated H-index: 110
Sources
Abstract
Objective:The aim of the present study was to evaluate the clinical implications of the 2016 International Study Group for Pancreatic Surgery (ISGPS) definition and classification of postoperative pancreatic fistula (POPF) using a single high-volume institutional cohort of patients undergone pancrea
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#1Claudio BassiH-Index: 110
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Background In 2005, the International Study Group of Pancreatic Fistula developed a definition and grading of postoperative pancreatic fistula that has been accepted universally. Eleven years later, because postoperative pancreatic fistula remains one of the most relevant and harmful complications of pancreatic operation, the International Study Group of Pancreatic Fistula classification has become the gold standard in defining postoperative pancreatic fistula in clinical practice. The aim of th...
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Objective: To evaluate and quantify surgical skill by grading surgical performance of the pancreaticojejunostomy from robotic pancreaticoduodenectomies (RPDs). We hypothesized that video grading of surgical performance would contribute to estimating risk of postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy. Background: POPF majorly contributes to pancreaticoduodenectomy morbidity. Risk scores [Fistula Risk Score (FRS) and Braga] derived from patient variables are validated fo...
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#1Thilo Hackert (Heidelberg University)H-Index: 57
#2Ulf Hinz (Heidelberg University)H-Index: 64
Last. Markus W. Büchler (Heidelberg University)H-Index: 173
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Background Postoperative pancreatic fistula (POPF) is the most important complication after pancreatic surgery. In 2005, the International Study Group of Pancreatic Surgery (ISGPS) introduced a standardized POPF definition with severity grading from A to C. In recent years, interventional drainage (ID) has become the standard of care for symptomatic postoperative fluid collections or undrained POPF. From the original definition, it is unclear whether ID is categorized as POPF grade B or C. There...
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Abstract Background A post‐operative pancreatic fistula (POPF) is a major cause of morbidity and mortality after a pancreaticoduodenectomy (PD). This systematic review aimed to identify all scoring systems to predict POPF after a PD, consider their clinical applicability and assess the study quality. Method An electronic search was performed of Medline (1946–2014) and EMBASE (1996–2014) databases. Results were screened according to Preferred Reporting Items for Systematic Reviews and Meta‐Analys...
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#1Claudio Bassi (Heidelberg University)H-Index: 110
#2Markus W. Büchler (Heidelberg University)H-Index: 173
Last. Michael G. SarrH-Index: 107
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#1Giuseppe Malleo (University of Verona)H-Index: 43
#2Alessandra Pulvirenti (University of Verona)H-Index: 11
Last. Claudio Bassi (University of Verona)H-Index: 110
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Background Postoperative pancreatic fistula (POPF) is the leading complication after partial pancreatic resection and is associated with increased length of hospital stay and resource utilization. The introduction of a common definition in 2005 by the International Study Group of Pancreatic Surgery (ISGPS), which has been since employed in the vast majority of reports, has allowed a reliable comparison of surgical results. Despite the systematic investigation of risk factors and of surgical tech...
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Backgrounds/Aims: Few reports have validated the clinical postoperative pancreatic fistula (PF) after distal pancreatectomy. The study intended to validate the predictability for clinical PF of drain amylase and lipase and to find out more appropriate postoperative day (POD) for diagnostic criterion of PF. Methods: A total of 154 patients underwent distal pancreatectomy. We used the clinical database registry system of the Gangnam Severance Hospital and Severance Hospital, Yonsei University Heal...
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#1Peter J. Allen (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 97
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Background Postoperative pancreatic fistula is a major contributor to complications and death associated with pancreatic resection. Pasireotide, a somatostatin analogue that has a longer half-life than octreotide and a broader binding profile, decreases pancreatic exocrine secretions and may prevent postoperative pancreatic fistula. Methods We conducted a single-center, randomized, double-blind trial of perioperative subcutaneous pasireotide in patients undergoing either pancreaticoduodenectomy ...
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#1Benjamin C. Miller (UPenn: University of Pennsylvania)H-Index: 5
#2John D. Christein (UAB: University of Alabama at Birmingham)H-Index: 35
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Abstract Background The Post‐operative Morbidity Index (PMI) is a quantitative utility measure of a complication burden created by severity weighting. The Fistula Risk Score (FRS) is a validated model that predicts whether a patient will develop a post‐operative pancreatic fistula (POPF). These novel tools might provide further discrimination of the ISGPF grading system. Methods From 2001 to 2012, 1021 pancreaticoduodenectomies were performed at four institutions. POPFs were categorized by ISGPF...
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#1Mark P. Callery (BIDMC: Beth Israel Deaconess Medical Center)H-Index: 66
#2Wande B. Pratt (WashU: Washington University in St. Louis)H-Index: 18
Last. Charles M. Vollmer (UPenn: University of Pennsylvania)H-Index: 67
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Background Clinically relevant postoperative pancreatic fistulas (CR-POPF) are serious inherent risks of pancreatic resection. Preoperative CR-POPF risk assessment is currently inadequate and rarely disqualifies patients who need resection. The best evaluation of risk occurs intraoperatively, and should guide fistula prevention and response measures thereafter. We sought to develop a risk prediction tool for CR-POPF that features intraoperative assessment and reveals associated clinical and econ...
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