What is New in Gastrointestinal Stromal Tumor?

Volume: 24, Issue: 5, Pages: 259 - 267
Published: Sep 1, 2017
Abstract
The classification "gastrointestinal stromal tumor" (GIST) became commonplace in the 1990s and since that time various advances have characterized the GIST lineage of origin, tyrosine kinase mutations, and mechanisms of response and resistance to targeted therapies. In addition to tyrosine kinase mutations and their constitutive activation of downstream signaling pathways, GISTs acquire a sequence of chromosomal aberrations. These include...
Paper Details
Title
What is New in Gastrointestinal Stromal Tumor?
Published Date
Sep 1, 2017
Volume
24
Issue
5
Pages
259 - 267
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