Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways
Abstract
Dietary, microbial, and inflammatory factors modulate the gut-brain axis and influence physiological processes ranging from metabolism to cognition. The gut epithelium is a principal site for detecting such agents, but precisely how it communicates with neural elements is poorly understood. Serotonergic enterochromaffin (EC) cells are proposed to fulfill this role by acting as chemosensors, but understanding how these rare and unique cell types...
Paper Details
Title
Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways
Published Date
Jun 1, 2017
Journal
Volume
170
Issue
1
Pages
185 - 198.e16
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