Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention
Abstract
Emerging evidence has linked the gut microbiome to human obesity. We performed a metagenome-wide association study and serum metabolomics profiling in a cohort of lean and obese, young, Chinese individuals. We identified obesity-associated gut microbial species linked to changes in circulating metabolites. The abundance of Bacteroides thetaiotaomicron, a glutamate-fermenting commensal, was markedly decreased in obese individuals and was...
Paper Details
Title
Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention
Published Date
Jun 19, 2017
Journal
Volume
23
Issue
7
Pages
859 - 868
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