Animal Models for Testing Antidotes Against an Oral Cyanide Challenge

: Cyanide (CN) is ubiquitous in many living organisms, commonly used in manufacturing processes (dyes, pigments, chelating agents, various nitriles, monomers, resins, fibers, case hardening, electroplating, extraction of precious metals, and fumigation), observed in accidental poisonings from natural or manmade products (smoke inhalation, cyanogens in apple seeds, peach pits, cherry pits, etc.) and as a possible terror threat agent. A higher...