Original paper
Manipulating DNA damage-response signaling for the treatment of immune-mediated diseases
Abstract
Significance Therapeutic immune suppression is essential for treating a variety of immune conditions, including autoimmune diseases, immunoregulatory disorders, and in transplantation. Reliance on broadly acting drugs carries substantial risks, and even pathway-specific agents are problematic, because most immune pathways have essential functions. The ideal form of immune suppression would be antigen-specific, suppressing an undesired immune...
Paper Details
Title
Manipulating DNA damage-response signaling for the treatment of immune-mediated diseases
Published Date
May 22, 2017
Volume
114
Issue
24