Regulation of Osteoclast Growth and Fusion by mTOR/raptor and mTOR/rictor/Akt

Volume: 5
Published: May 18, 2017
Abstract
Osteoclasts are giant bone cells formed by fusion from monocytes and uniquely capable of a complete destruction of mineralized tissues. Previously, we have demonstrated that in energy-rich environment not only osteoclast fusion index (the number of nuclei each osteoclast contains), but also cytoplasm volume per single nucleus was increased. The goal of this study was to investigate the regulation of metabolic sensor mTOR during osteoclast...
Paper Details
Title
Regulation of Osteoclast Growth and Fusion by mTOR/raptor and mTOR/rictor/Akt
Published Date
May 18, 2017
Volume
5
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