Review paper
Alkaline phosphatase: a novel treatment target for cardiovascular disease in CKD
Abstract
Cardiovascular disease is the main cause of early death in the settings of chronic kidney disease (CKD), type 2 diabetes mellitus (T2DM), and ageing. Cardiovascular events can be caused by an imbalance between promoters and inhibitors of mineralization, which leads to vascular calcification. This process is akin to skeletal mineralization, which is carefully regulated and in which isozymes of alkaline phosphatase (ALP) have a crucial role. Four...
Paper Details
Title
Alkaline phosphatase: a novel treatment target for cardiovascular disease in CKD
Published Date
May 15, 2017
Journal
Volume
13
Issue
7
Pages
429 - 442
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