The contribution of direct patient reported ADRs to drug safety signals in the Netherlands from 2010 to 2015

Purpose The purpose of this study was to investigate the contribution of patient reports to signals sent by the Netherlands Pharmacovigilance Centre Lareb to the Dutch Medicines Evaluation Board and to determine if there are certain types of signals where patient report add a distinct contribution. Method All signals from 2010 until 2015 were included. First, we investigated how many patient reports were present in the signals and the...