Original paper
The ErbB family and androgen receptor signaling are targets of Celecoxib in prostate cancer
Abstract
Inflammation plays a central role in prostate cancer (PCa) development through significant crosstalk between the COX-2-ErbB family receptor network and androgen receptor (AR)-EGFR signaling pathways. The purpose of this work was to determine the ability of the COX-2 inhibitor Celecoxib to modulate the EGFR-AR signaling pathway in androgen-dependent PCa cells and to provide a rationale for its beneficial use in chemopreventive strategies....
Paper Details
Title
The ErbB family and androgen receptor signaling are targets of Celecoxib in prostate cancer
Published Date
Aug 1, 2017
Journal
Volume
400
Pages
9 - 17
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Notes
History