Treating head and neck cancer: for better or for worse?

Head and neck cancer is a heterogenous group of diseases arising from a range of anatomical sites with distinct histopathologies and an unpredictable presentation. Over half a million new cases are diagnosed globally each year, with the majority being of squamous cell origin arising from the mucosal lining of the oral cavity, oropharynx, larynx, and hypopharynx, and often related to tobacco and alcohol misuse. Although surgery and...