The Race of 10 Synthetic RNAi-Based Drugs to the Pharmaceutical Market
Abstract
Ten years after Fire and Melo’s Nobel Prize for discovery of gene silencing by double-stranded RNA, a remarkable progress was achieved in RNA interference (RNAi). Changes in the chemical structure of synthetic oligonucleotides make them more stable and specific, and new delivery strategies became progressively available. The attention of pharmaceutical industry rapidly turned to RNAi, as an opportunity to explore new drug targets. This review...
Paper Details
Title
The Race of 10 Synthetic RNAi-Based Drugs to the Pharmaceutical Market
Published Date
Apr 7, 2017
Journal
Volume
34
Issue
7
Pages
1339 - 1363
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